Know More About This Test

SGPT, also known as ALT (Alanine Aminotransferase), is a liver enzyme found mainly in liver cells. When liver cells are damaged or inflamed, SGPT is released into the bloodstream.

This test is a sensitive marker of liver injury and is commonly used to detect hepatitis, fatty liver disease, and drug-induced liver damage.

Why Is This Test Recommended?

You may be advised this test to:

• Evaluate liver health

• Diagnose hepatitis or fatty liver

• Monitor liver-toxic medications

• Investigate unexplained fatigue or jaundice

• Screen for liver disease in routine check-ups

Understanding SGPT

SGPT rises earlier than many other liver enzymes in liver injury, making it a valuable early indicator. It is highly specific to liver damage and helps assess the severity and progression of liver conditions.

Symptoms or Conditions That May Require This Test

• Yellowing of skin or eyes (jaundice)

• Dark urine

• Abdominal pain or discomfort

• Chronic alcohol use

• Unexplained fatigue or weakness

Why Do I Need This Test?

To detect liver damage early, monitor treatment effectiveness, and prevent progression to serious liver disease.

How Do I Prepare for the Test?

Fasting may be advised depending on whether other tests are included. Avoid alcohol 24–48 hours prior to testing.

How Is the Test Performed?

A blood sample is collected from a vein in your arm.

What Happens After the Test?

Results are interpreted alongside other liver function tests and clinical findings to determine the cause and extent of liver damage.

When Should I Consult a Doctor?

If SGPT levels are persistently elevated or if you experience symptoms of liver disease.

Risks Associated With This Test

Minimal risk related to blood draw only.

Lifestyle Tips

• Avoid or limit alcohol consumption

• Maintain healthy weight

• Follow a liver-friendly diet low in fats and processed foods

• Exercise regularly

• Avoid unnecessary medications and supplements

What Does This Test Measure?

The test measures SGPT (ALT) enzyme levels in the blood, indicating liver cell health and function.

What Do the Results Mean?

High SGPT levels suggest liver inflammation or damage. Normal levels indicate healthy liver function.

What Should I Do If Results Are Abnormal?

Further evaluation, additional liver tests, imaging studies, and lifestyle modifications may be required based on your doctor's recommendations.

Factors That May Affect Results

Alcohol consumption, obesity, certain medications, herbal supplements, and intense exercise.

Frequently Asked Questions (FAQs)

• Is SGPT specific to liver?
  Mostly yes; SGPT is predominantly found in liver cells, making it highly specific for liver damage, though small amounts exist in other tissues.

• Can mild elevation be normal?
  Sometimes; minor elevations can occur temporarily due to medications, vigorous exercise, or benign conditions and may not indicate serious liver disease.

• Does exercise affect SGPT?
  Intense exercise may raise it; strenuous physical activity can cause temporary mild elevation in SGPT levels.

• Is fasting required?
  Sometimes; fasting may be recommended if SGPT is part of a comprehensive metabolic panel or lipid profile.

• Can SGPT normalize?
  Yes, with treatment; SGPT levels can return to normal with appropriate treatment, lifestyle changes, and removal of the underlying cause.